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December 10th, 2003 - Volume 25 - Issue 23
pp: 4-76

Report: Caution Urged in Testosterone Clinical TrialsProstate Cancer Risk Key Concern for Older Men

Eastman, Peggy

Oncology Times. 25(23):6-10, December 10th, 2003.

Due to concerns about increasing the risk of prostate cancer, clinical trials of the benefits of testosterone-replacement therapy for older men should first be done in small, short-term investigations, a new report concludes.

Provocative Study Calls Into Question Existence of Graft-vs-Lymphoma Effect

Goodman, Alice

Oncology Times. 25(23):32,37, December 10th, 2003.

A retrospective review of syngeneic, allogeneic, and autologous transplants for NHL surprisingly found no evidence for a GvL effect. The results did, however, provide indirect support of the benefits of purging for patients undergoing autologous hematopoietic stem-cell transplants for low-grade NHL.

Delaying Chemo Appropriate for Certain Type of Non-Hodgkin's Lymphoma

Laino, Charlene

Oncology Times. 25(23):22, December 10th, 2003.

Delaying chemotherapy until symptoms develop may be a suitable option for patients with asymptomatic, advanced low-grade NHL, particularly those over 70 years old, new data suggest. Page 22

Even in Patients with Severe Bone Pain, Single-Dose Radiation Gives Effective Palliation

Peck, Peggy

Oncology Times. 25(23):25, December 10th, 2003.

(1) Even in Patients with Severe Bone Pain, Single-Dose RT Gives Effective Palliation; (2) Routine Use of Regional RT May Result in Overtreatment; (3) Radiation-Associated Erectile Dysfunction: Viagra Induces Good Response; (4) Breast Reconstruction Can Be Safe Before RT; (5) Whole-Breast Irradiation May Offer Long-Term Benefits; and (6) Ki-67 Staining Index Helps to Predict Outcome in Prostate Cancer Patients.