In its eighth annual ranking of the Top 10 Medical Innovations that will have a major impact on improving patient care within the next year—selected by a panel of Cleveland Clinic physicians and scientists—two emerging technologies on the list were cancer-related. Those two innovations were:
- Genome-guided solid tumor diagnostics (genomic-based cancer tests), which, without surgery, can analyze the genes in a specific tumor to predict the biology and aggressiveness of the cancer; and
- B-cell receptor pathway inhibitors for blood cancer treatments, which block the signals that cause cancer cells to grow and divide uncontrollably in specific pathways, ultimately stopping cancer progression and preserving normal, healthy cells.
To receive consideration, nominated technologies had to: have had a significant clinical impact, offer significant patient benefit in comparison to current practices, and have a high user-related functionality that improves health care delivery; have a high probability of commercial success; either be in clinical trials or be available on the market in 2014; and have a significant human interest in its application or benefits. Seventy-six emerging technologies nominated by Cleveland Clinic staff were considered for the list.
The nominations were reviewed by two independent panels of Cleveland Clinic physicians. The two panels voted first on their own list of finalists and then on a combined list to narrow the field to the 10 innovations that appeared the final list.