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Antenatal Blood Pressure for Prediction of Preeclampsia, Preterm Birth, and Small for Gestational Age Babies

Development and Validation in 2 General Population Cohorts

Macdonald-Wallis, C.; Silverwood, R.J.; de Stavola, B.L.; Inskip, H.; Cooper, C.; Godfrey, K.M.; Crozier, S.; Fraser, A.; Nelson, S.M.; Lawlor, D.A.; Tilling, K.

doi: 10.1097/01.aoa.0000489474.37651.10
Mother, Fetus, Neonate

(BMJ. 2015;351:h5948)

Preeclampsia is one of the most common complications of pregnancy and is associated with adverse outcomes, such as maternal and fetal mortality, intrauterine growth restriction, and preterm birth. The aim of this study was to determine whether the addition of routine antenatal blood pressure measurements between 20 and 36 weeks of gestation could improve the predictive value of existing prediction models for preeclampsia and its associated adverse outcomes, which only include a blood pressure measurement from the first antenatal visit.

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK

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