Postoperative AnalgesiaA Multimodal Approach to Reducing Post-Cesarean Opioid Use: A Quality Improvement InitiativeLlarena, N.C.; Krivanek, K.; Yao, M.; Kim, D.D.; Devarajan, J.; Ayad, S.; Chiang, E. Author Information Department of Obstetrics and Gynecology, Women’s Health Institute, Cleveland Clinic, Cleveland, OH Obstetric Anesthesia Digest 43(2):p 102, June 2023. | DOI: 10.1097/01.aoa.0000927952.72076.83 Buy Metrics Abstract (BJOG: Int J Obstet Gynaecol. 2022;129:1583–1590) Opioid administration following cesarean delivery is common in the United States, but the number of opioids prescribed is often higher than needed to control pain. Opioid overdose deaths among reproductive-age women have increased since 1999. Opioids also are associated with adverse effects and outcomes for mothers and neonates. A multi-modal approach using acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs) is recommended by American College of Obstetricians and Gynecologists and the American Society of Anesthesiologists. These methods have been shown to reduce opioid use and adequately manage pain but have not been widely adopted by clinicians. This study evaluated a four-part quality improvement initiative, including nursing education, designed to reduce inpatient and outpatient opioid use and prescribing patterns. Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.