Anesthesia and Analgesia: Regional AnesthesiaIntrathecal 2-Chloroprocaine 3% Versus Hyperbaric Bupivacaine 0.75% for Cervical Cerclage: A Double-blind Randomized Controlled TrialLee, A.; Shatil, B.; Landau, R.; Menon, P.; Smiley, R. Author Information Department of Anesthesiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY; and Department of Anesthesiology, Emory University, Atlanta Georgia; and Department of Bioengineering University of Pittsburgh, Pittsburgh, PA Obstetric Anesthesia Digest: September 2022 - Volume 42 - Issue 3 - p 149-151 doi: 10.1097/01.aoa.0000853652.27886.93 Buy Metrics Abstract (Anesth Analg. 2022;134:624–632) Cervical cerclage, an operation designed to reduce preterm delivery and improve perinatal outcomes, often utilizes spinal anesthesia. While the benefits of spinal anesthesia are well documented, an intrathecal local anesthetic agent, such as 2-chloroprocaine (2-CP), could shorten postanesthesia care unit stay as it has a fast onset and short duration. Currently, bupivacaine is commonly used during spinal anesthesia because of historical concern regarding 2-CP’s safety. This study randomly compared the outcome of 2-CP 3% 50 mg and hyperbaric bupivacaine 0.75% 9 mg on dermatomal level, sensory block resolution, ability to ambulate and void, and motor blockade. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.