Editor's PicksComparison of Chloroprocaine Versus Lidocaine With Epinephrine, Sodium Bicarbonate, and Fentanyl for Epidural Extension Anesthesia in Elective Cesarean Delivery: A Randomized, Triple-blind, Noninferiority StudySharawi, N.; Bansal, P.; Williams, M.; Spender, H.; Mhyre, J. Author Information Departments of Anesthesiology and Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR Obstetric Anesthesia Digest 42(3):p 105-107, September 2022. | DOI: 10.1097/01.aoa.0000853444.72326.9d Buy Metrics Abstract (Anesth Analg. 2021;132: 666–675) Neuraxial analgesia is utilized in over 70% of labors in the United States. The authors of this study report a general consensus among their local and nonlocal peers that 3% chloroprocaine or CP, a local anesthetic with a quick preparation time, and 2% lidocaine, epinephrine, bicarbonate, and fentanyl, or LEBF, which needs additional preparation time, have similar onset times when used to convert epidural pain relief to epidural anesthesia for cesarean delivery (CD). To their knowledge, no study has confirmed this assumption. This study analyzes the onset times of CP and LEBF. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.
