Anesthesia and Analgesia: Regional AnesthesiaObstetric Neuraxial Anesthesia at Low Platelet Counts in the Context of Immune Thrombocytopenia: A Systematic Review and Meta-analysisBailey, L.J.; Nadine Shehata, N.; De France, B.; Carvalho, J.C.A.; Malinowski, A.K.Author Information Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine, Mount Sinai Hospital, Toronto, ON, Canada Obstetric Anesthesia Digest: September 2020 - Volume 40 - Issue 3 - p 165-166 doi: 10.1097/01.aoa.0000693856.20785.be Buy Metrics Abstract (Can J Anesth. 2019;66:1396–1414) Immune thrombocytopenia purpura (ITP) is a rare autoimmune condition marked by a low platelet count, typically <100×109/L. It may initially present during the preconception or antenatal periods. Most women are asymptomatic, but some may experience epistaxis, petechiae, easy bruising, or mucosal bleeding. Consensus on a safe threshold for platelet counts for placement of neuraxial anesthesia in pregnancy is unclear. The American Society of Anesthesiologists recommends an individualized approach to determine the risk of excessive bleeding without suggesting a minimum platelet threshold. The aim of this study was to examine obstetric neuraxial anesthesia (OBNA) outcomes in patients with platelet counts <100×109/L in the context of primary ITP. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.