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I. ALTERNATIVE METHODS OF ANALGESIA Preoperative Cesarean Delivery Intravenous Acetaminophen Treatment for Postoperative Pain Control

A Randomized Double-blinded Placebo Control Trial

Towers, C.V.; Shelton, S.; van Nes, J.; Gregory, E.; Liske, E.; Smalley, A.; Mobley, E.; Faircloth, B.; Fortner, K.B.

Obstetric Anesthesia Digest: December 2018 - Volume 38 - Issue 4 - p 222
doi: 10.1097/
Anesthesia and Analgesia: Alternative Methods of Analgesia

(Am J Obstet Gynecol. 2018;218:353.e1–353.e4)

Most patients first encounter opioid medications after surgery or during an acute pain episode. The ongoing opioid use disorder epidemic in the United States has prompted research to minimize opioid treatment in the postsurgical setting. Nonobstetrical studies have reported improved pain scores and decreased opioid use after surgery with the preoperative administration of intravenous (IV) acetaminophen. The primary outcome in the current study was to examine if maternal opioid use was significantly less in the postoperative period when preoperative IV acetaminophen was given. Secondary outcomes included hospital length of stay, pain scores, and cord blood acetaminophen levels.

Departments of Obstetrics and Gynecology, University of Tennessee Medical Center, Knoxville, TN

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