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II. REGIONAL ANALGESIA Dose-Response Curves for Intrathecal Bupivacaine, Levobupivacaine and Ropivacaine Given for Labor Analgesia in Nulliparous Women

Ngan Kee, W.D.; Ng, F.F.; Khaw, K.S.; Tang, S.P.Y.; Koo, A.G.P.

doi: 10.1097/01.aoa.0000547324.09720.6c
Anesthesia and Analgesia: Regional Analgesia

(Reg Anesth Pain Med. 2017;42(6):788–792)

As part of the combined spinal-epidural (CSE) technique, bupivacaine, levobupivacaine and ropivacaine are often administered intrathecally to establish labor analgesia with a rapid onset of action. Data on the dose-response relationships of bupivacaine, levobupivacaine and ropivacaine for this purpose are limited. This double-blind, random allocation, graded dose-response study aimed to describe dose-response curves for the intrathecal use of these drugs.

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, Hong Kong, People’s Republic of China

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