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Food and Drug Administration Warning on Anesthesia and Brain Development

Implications for Obstetric and Fetal Surgery

Olutoye, O.A.; Baker, B.W.; Belfort, M.A.; Olutoye, O.O.

doi: 10.1097/01.aoa.0000547276.94540.6a
Editorials and Reviews

(Am J Obstet Gynecol. 2018;218(1):98–102)

The United States Food and Drug Administration has warned against the use of general anesthetics and sedation medications for >3 hours in pregnant women in the third trimester and children younger than 3 years old. The anesthetics agents listed included midazolam, propofol, and inhalational anesthetics (isoflurane, sevoflurane, and desflurane). They claim these agents may affect the development of children’s brains.

Departments of Anesthesiology Baylor College of Medicine, Texas Children’s Fetal Center; Texas Children’s Hospital, Houston, TX

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