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Antidepressant Use During Pregnancy and Psychiatric Disorders in Offspring: Danish Nationwide Register-based Cohort Study

Liu, X.; Agerbo, E.; Ingstrup, K.G.; Musliner, K.; Meltzer-Brody, S.; Bergink, V.; Munk-Olsen, T.

Obstetric Anesthesia Digest: June 2018 - Volume 38 - Issue 2 - p 77–78
doi: 10.1097/01.aoa.0000532270.29483.d8
Epidemiologic Reports, Surveys

(BMJ. 2017;358:j3668)

Antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), are prescribed during pregnancy and are considered safe. Recent studies have raised concerns regarding the long-term neurodevelopmental effects, such as autism and attention-deficit/hyperactivity disorder, of these medications on the offspring. However, gaps exist in the knowledge of antidepressant use during pregnancy and risk of psychiatric disorders in the offspring. This population-based cohort study was performed to investigate the association between in utero antidepressant exposure and overall risk of psychiatric disorders in children.

National Center for Register-based Research, Aarhus University, Aarhus, Denmark

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