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The Significance of Base Deficit in Acidemic Term Neonates

Knutzen, L.; Svirko, E.; Impey, L.

doi: 10.1097/01.aoa.0000489433.86071.1d
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(Am J Obstet Gynecol. 2015;213(3):373.e1–e7)

A lack of oxygen during the intrapartum period is a well-known and significant factor leading to cerebral palsy and mortality in infants. The degree of risk can be estimated after delivery by examining pH levels in the umbilical artery. An arterial pH of <7.00 along with a base deficit of 12 mmol/L or higher is believed to be particularly significant in predicting morbidity. The authors of this study have attempted to evaluate this association, hypothesizing that the level of arterial base deficit does not have any extra predictive value in acidemic neonates beyond what can be learned from the arterial pH.

Oxford Fetal Medicine Unit, Women’s Center, John Radcliffe Hospital, Oxford, UK

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