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Scheduled Acetaminophen With As-needed Opioids Compared With As-needed Acetaminophen Plus Opioids for Postcesarean Pain Management

Valentine, A.R.; Carvalho, B.; Lazo, T.A.; Riley, E.T.

doi: 10.1097/01.aoa.0000482647.00882.aa
General Anesthesia: Postoperative Analgesia

(Int J Obstet Anesth. 2015;24:210–216)

Postoperative multimodal regimens like oral opioid-acetaminophen combination drugs can produce adverse maternal opioid-related side effects. Uncoupling these 2 drugs and administering them separately on a scheduled basis (acetaminophen plus as-needed opioids) may thereby be advantageous and lead to decreased opioid use. In the present study, the authors compared opioid use for scheduled acetaminophen plus as-needed opioid regimens with as-needed opioid-acetaminophen combination drug regimens.

Stanford University School of Medicine; Department of Anesthesia, Stanford University Medical Center, Stanford, CA

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