Editor’s PicksA Randomized, Double-blinded Trial of a “Rule of Threes” Algorithm Versus Continuous Infusion of Oxytocin During Elective Cesarean DeliveryKovacheva, V.P.; Soens, M.A.; Tsen, L.C.Author Information Department of Anesthesiology, Perioperative, and Pain Medicine, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA Obstetric Anesthesia Digest: June 2016 - Volume 36 - Issue 2 - p 61-63 doi: 10.1097/01.aoa.0000482592.65511.c9 Buy Metrics Abstract (Anesthesiology. 2015;123:92–100) Oxytocin is commonly used to improve uterine tone during cesarean delivery. However, if administered too quickly or in high doses it can lead to such adverse effects as hemodynamic instability, cardiovascular collapse, and even death. There are also currently no established recommended doses, timing, or rates of administration. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.