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The Effect of Bupivacaine With Fentanyl Temperature on Initiation and Maintenance of Labor Epidural Analgesia: A Randomized Controlled Study

Sviggum, H.P.; Yacoubian, S.; Liu, X.; Tsen, L.C.

doi: 10.1097/01.aoa.0000479529.43813.2e
Anesthesia and Analgesia: Regional Analgesia
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(Int J Obstet Anesth. 2015;24(1):15–21)

Epidural analgesia is one of the most effective methods of labor analgesia, but its initial onset can take 15 to 25 minutes. In addition, breakthrough pain can occur and shivering is a relatively common side effect. Recent studies have demonstrated that the epidural administration of warmed (body temperature as opposed to room temperature) bupivacaine results in a surgical anesthesia blockade that has a more rapid onset and more effective anesthesia.

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA

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