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Methylnaltrexone to Prevent Intrathecal Morphine-induced Pruritus After Cesarean Delivery: A Multicenter, Randomized Clinical Trial

Paech, M.; Sng, B.; Ng, L.; Nathan, E.; Sia, A.; Carvalho, B.

doi: 10.1097/01.aoa.0000479533.36189.06
Anesthesia and Analgesia: Postoperative Analgesia

(Br J Anaesth. 2015;114(3):469–476)

Intrathecal morphine is commonly administered to patients after abdominal surgery, such as cesarean delivery. However, this method of analgesia is associated with a high risk of morphine-induced pruritus, a side effect that currently lacks effective methods of prevention or treatment.

Pharmacology, Pharmacology and Anaesthesiology Unit, School of Medicine and Pharmacology, The University of Western Australia, Crawley, WA, Australia

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