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Investigating Fetal Growth Restriction and Perinatal Risks in Appropriate for Gestational Age Infants

Using Cohort and Within-Sibling Analyses

Cnattingius, S.; Kramer, M. S.; Norman, M.; Ludvigsson, J. F.; Fang, F.; Lu, D.

Obstetrical & Gynecological Survey: November 2019 - Volume 74 - Issue 11 - p 631–633
doi: 10.1097/OGX.0000000000000741
OBSTETRICS: FETAL DIAGNOSIS AND THERAPY
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(Abstracted from BJOG 2019;126(7):842–850)

Fetal growth restriction, defined as fetal growth below expectations, is statistically measured by a cutoff of birthweight for gestational age. Small-for-gestational-age (SGA) birth, however, is not always linked with fetal growth restriction: SGA infants may have reached their growth potential and just be small, while larger, non-SGA infants sometimes fail to reach their growth potential.

Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden (S.C.); Departments of Pediatrics (M.S.K.), and Epidemiology, Biostatistics, and Occupational Health (M.S.K.), McGill University Faculty of Medicine, Montreal, Quebec, Canada; Division of Pediatrics, Department of Clinical Science, Intervention, and Technology (M.N.), and Department of Neonatology (M.N.), Karolinska University Hospital, and Department of Medical Epidemiology and Biostatistics (J.F.L., F.F., D.L.), Karolinska Institutet, Stockholm; Department of Pediatrics, Orebro University Hospital, Orebro (J.F.L.), Sweden; and Centre of Public Health Sciences, Faculty of Medicine, University of Iceland, Reykjavik, Iceland (D.L.)

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