(Abstracted from BJOG 2019;126(5):556–567)
Around the world, approximately 15 million pregnancies each year end in preterm birth (before 37 weeks' gestation), a major contributor to child morbidity and mortality. To reduce the risk of preterm birth for women at increased risk, interventions include progesterone, cervical cerclage, and cervical pessary.
Department of Obstetrics and Gynecology, McMaster University, Hamilton (A.J., S.D.M.); Provincial Council for Maternal and Child Health, Toronto (O.L.); and Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton (J.B.), Ontario, Canada