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Pregnancy-Adapted YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism

van der Pol, Liselotte M.; Tromeur, Cecile; Bistervels, Ingrid M.; Ni Ainle, Fionnuala; van Bemmel, Thomas; Bertoletti, Laurent; Couturaud, Francis; van Dooren, Yordi P. A.; Elias, Antoine; Faber, Laura M.; Hofstee, Herman M. A.; van der Hulle, Tom; Kruip, Marieke J. H. A.; Maignan, Maxime; Mairuhu, Albert T. A.; Middeldorp, Saskia; Nijkeuter, Mathilde; Roy, Pierre-Marie; Sanchez, Olivier; Schmidt, Jeannot; ten Wolde, Marije; Klok, Frederikus A.; Huisman, Menno V. for the Artemis Study Investigators

Obstetrical & Gynecological Survey: August 2019 - Volume 74 - Issue 8 - p 460–462
doi: 10.1097/01.ogx.0000577816.58861.db
OBSTETRICS: MEDICAL COMPLICATIONS OF PREGNANCY
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(Abstracted from N Engl J Med 2019;380:1139–1149)

Acute pulmonary embolism is one of the leading causes of maternal death, with the overall incidence reported to be 1.72 cases per 1000 deliveries, accounting for approximately 1 death in every 100,000 deliveries. Since the D-dimer test has low specificity and sensitivity, it is common for pregnant women with suspected pulmonary embolism to undergo computed tomography (CT) pulmonary angiography or ventilation-perfusion (V/Q) scanning, both of which involve radiation exposure to the mother and fetus.

Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden (L.M.v.d.P., T.v.d.H., F.A.K., M.V.H.); Department of Internal Medicine, Haga Teaching Hospital (L.M.v.d.P., A.T.A.M.); Department of Internal Medicine, Haaglanden Medical Center (H.M.A.H.); Department of Vascular Medicine, Amsterdam University Medical Center, University of Amsterdam, Amsterdam Cardiovascular Sciences (I.M.B., S.M.), Amsterdam; Department of Internal Medicine, Flevo Hospital, Almere (I.M.B., M.t.W.); Department of Internal Medicine, Gelre Hospital, Apeldoorn (T.v.B.); Department of Pulmonology, Groene Hart Hospital, Gouda (Y.P.A.v.D.); Department of Internal Medicine, Red Cross Hospital, Beverwijk (L.M.F.); Department of Hematology, Erasmus University Medical Center, Rotterdam (M.J.H.A.K.); Department of Internal Medicine, University Medical Center Utrecht, Utrecht (M.N.), The Netherlands; Department of Internal Medicine and Chest Diseases, Brest Hospital Center, Groupe d'Etude de Thrombose de Bretagne Occidentale, University of Brest, EA 3878, CIC-INSERM 1412, University of Brest, Brest (C.T., F.C.); Service de médecine vasculaire et thérapeutique, Centre Hospitalier Universitaire (CHU) Saint Etienne, INSERM CIC-1408, INSERM Unité 1059, Equipe Dysfonction Vasculaire et Hémostase, Université Jean-Monnet, Saint Etienne (L.B.); Department of Vascular Medicine, Sainte Musse Hospital, Toulon (A.E.); Emergency Department, CHU Grenoble-Alpes, Hypoxy-Physiopathology laboratory HP2 INSERM 1042, Grenoble (M.M.); Emergency Department, CHU d'Angers, UFR Santé, Université d'Angers, Institut Mitovasc, UMR CNRS 6015 UMR INSERM 1083, Anger (P.-M.R.); Department of Pulmonary Disease and Intensive Care Unit, Hôpital Européen Georges Pompidou, Assistance Publique–Hôpitaux de Paris, Université Paris Descartes, Faculté de Médecine, Université Sorbonne Paris Cité, INSERM UMR S 1140, Paris (O.S.); Emergency Department, CHU de Clermont-Ferrand, Clermont-Ferrand (J.S.), France; School of Medicine, University College Dublin (F.N.A.); and Department of Haematology, Rotunda Hospital Dublin, INViTE Network (F.N.A.), Dublin, Ireland

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