(Abstracted from JAMA 2019;321(6):588–601)
Perinatal depression is a common condition that was estimated in 2012 to affect more than 180,000 new mothers (11.5%) annually in the United States and that can have serious impact on mother and infant well-being. Numerous interventions have been proposed to prevent perinatal depression, but there is no commonly agreed-on prevention method, creating a scenario with substantial variation in clinical practice.
Kaiser Permanente Research Affiliates Evidence-Based Practice Center, Center for Health Research, Kaiser Permanente, Portland, OR (E.O., C.A.S., M.L.H., E.C.); and University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC (B.N.G.)