(Abstracted from Fertil Steril 2019;111(1):86–96)
Initial phases of embryonic development have a high requirement for ATP, and evidence shows that oocytes with high ATP levels enhance implantation of the human embryo. Decreased bioenergetic capacity in oocytes has been found to be a primary contributor to declining embryo quality with advancing maternal age or in women with premature ovarian aging.
IVI-RMA Valencia (E.L., M.J.d.l.S., S.H., M.J.E., A.M., A.P.) and IVI Foundation (E.L., M.J.d.l.S., S.H., M.J.E., A.B.), Valencia, Spain; and IVI Rome, Rome, Italy (A.P.)