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Application of Cell-Free DNA Analysis to Cancer Treatment

Corcoran, Ryan B.; Chabner, Bruce A.

Obstetrical & Gynecological Survey: April 2019 - Volume 74 - Issue 4 - p 204–206
doi: 10.1097/01.ogx.0000554379.46945.9e

(Abstracted from N Engl J Med 2018;379(18):1754–1765)

Tumor biopsies represent the standard for cancer diagnosis and the primary method for molecular testing to guide the selection of precision therapies. Liquid biopsies, particularly those involving cell-free DNA (cfDNA) from plasma, are rapidly emerging as an important and minimally invasive adjunct to standard tumor biopsies and, in some cases, even a potential alternative approach.

Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA

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