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Screening for Syphilis Infection in Pregnant Women

Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

Lin, Jennifer S.; Eder, Michelle L.; Bean, Sarah I.

Obstetrical & Gynecological Survey: February 2019 - Volume 74 - Issue 2 - p 75–76
doi: 10.1097/01.ogx.0000553101.60544.68
OBSTETRICS: INFECTIOUS DISEASE
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(Abstracted from JAMA 2018;320(9):918–925)

Congenital syphilis is an infectious disease caused by the vertical transmission of Treponema pallidum; thus, prevention and detection of congenital syphilis depend on the identification of syphilis in pregnant women. Two screening protocols are commonly used: the traditional screening algorithm (ie, nontreponemal testing with reflex to treponemal testing) and the reverse sequence screening algorithm (ie, treponemal testing with reflex to nontreponemal testing).

Kaiser Permanente Research Affiliates Evidence-Based Practice Center, Center for Health Research, Kaiser Permanente, Portland, OR

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