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Evaluation of Comprehensive Chromosome Screening Platforms for the Detection of Mosaic Segmental Aneuploidy

Goodrich, David; Xing, Tongji; Tao, Xin; Lonczak, Agnieszka; Zhan, Yiping; Landis, Jessica; Zimmerman, Rebekah; Scott, Richard T. Jr; Treff, Nathan R.

Obstetrical & Gynecological Survey: February 2019 - Volume 74 - Issue 2 - p 88–89
doi: 10.1097/OGX.0000000000000647
GYNECOLOGY: GENETICS
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(Abstracted from J Assist Reprod Genet 2017;34:975–981)

Advancements in the efficacy of comprehensive chromosomal screening (CCS), namely, the ability to detect aneuploidy in all 24 human chromosomes, have established it as a cornerstone of infertility care. Recently, the development of high-throughput, massively parallel sequencing for use with CCS has led to highly accurate, simultaneous screening of multiple samples.

Reproductive Medicine Associates of New Jersey (D.G., T.X., R.T.S., N.R.T.); and Foundation for Embryonic Competence (X.T., A.L., Y.Z., J.L., R.Z.), Basking Ridge, NJ

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