(Abstracted from J Perinatol 2018;38:788–796)
Trisomy 13 (T13) and 18 (T18) are chromosomal anomalies that have historically been considered lethal, but this notion has been questioned within the last decade by physicians, ethicists, and families. The literature has focused on the commonly described negative parental experience of prenatal and neonatal counseling and the extent of medical and surgical interventions that children with these conditions receive, their survival, and neurodevelopmental outcomes.
Departments of Pediatrics (P.W., K.A., S.L.) and Obstetrics and Gynecology (E.P.), Medical College of Wisconsin, Milwaukee, WI