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Periconception Glycemic Control in Women With Type 1 Diabetes and Risk of Major Birth Defects

Population-Based Cohort Study in Sweden

Ludvigsson, Jonas F.; Neovius, Martin; Söderling, Jonas; Gudbjörnsdottir, Soffia; Svensson, Ann-Marie; Franzén, Stefan; Stephansson, Olof; Pasternak, Björn

Obstetrical & Gynecological Survey: December 2018 - Volume 73 - Issue 12 - p 667–669
doi: 10.1097/01.ogx.0000549659.04855.5c
OBSTETRICS: MEDICAL COMPLICATIONS OF PREGNANCY

(Abstracted from BMJ 2018;362:k2638)

Poor glycemic control has been linked to both immediate (eg, ketoacidosis) and long-term (eg, mortality and cardiovascular disease) complications in people with type 1 diabetes. The risk of pregnancy-related complications is of particular relevance to women with type 1 diabetes.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm (J.F.L.); Department of Pediatrics, Örebro University Hospital, Örebro (J.F.L.), Sweden; Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, City Hospital, Nottingham, United Kingdom (J.F.L.); Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY (J.F.L.); Clinical Epidemiology Division, Department of Medicine, Karolinska Institutet, Solna (M.N., J.S., O.S., B.P.); The National Diabetes Register, Centre of Registers Västra Götaland, Västra Götaland (S.G., A.-M.S., S.F.); Sahlgrenska Academy, Institute of Medicine, Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg (S.G.); Department of Women's and Children's Health, Karolinska Institutet, Stockholm (O.S.), Sweden; and Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark (B.P.)

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