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Meta-analysis on the Effect of Aspirin Use for Prevention of Preeclampsia on Placental Abruption and Antepartum Hemorrhage

Roberge, Stephanie; Bujold, Emmanuel; Nicolaides, Kypros H.

Obstetrical & Gynecological Survey: October 2018 - Volume 73 - Issue 10 - p 553–555
doi: 10.1097/OGX.0000000000000609
OBSTETRICS: PRECONCEPTION AND PRENATAL CARE

(Abstracted from Am J Obstet Gynecol 2018;218:483–489)

Impaired placentation in the first 16 weeks of pregnancy is associated with increased risk of subsequent development of preeclampsia, birth of small-for-gestational-age (SGA) neonates, and placental abruption. Previous studies reported that prophylactic use of aspirin reduces the risk of preeclampsia and SGA neonates with no significant effect on placental abruption.

Harris Birthright Research Centre of Fetal Medicine, Fetal Medicine Research Institute, King's College Hospital, London, United Kingdom (S.R., K.H.N.); and Department of Obstetrics and Gynecology and Department of Social and Preventive Medicine, Faculty of Medicine, Université Laval, Quebec City, Quebec, Canada (E.B.)

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