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Cognitive Outcomes of Children Born Extremely or Very Preterm Since the 1990s and Associated Risk Factors

A Meta-analysis and Meta-regression

Twilhaar, E. Sabrina; Wade, Rebecca M.; de Kieviet, Jorrit F.; van Goudoever, Johannes B.; van Elburg, Ruurd M.; Oosterlaan, Jaap

Obstetrical & Gynecological Survey: October 2018 - Volume 73 - Issue 10 - p 562–563
doi: 10.1097/01.ogx.0000547169.91377.70

(Abstracted from JAMA Pediatr 2018;172(4):361–367)

Despite apparent progress in perinatal care, children born extremely preterm or very preterm (EP/VP) remain at high risk of cognitive deficits, and long-term morbidity rates have not decreased. Extremely preterm or very preterm birth (<32 weeks of gestation) is associated with higher risks of motor, learning, and behavior problems and, particularly, cognitive impairment.

Clinical Neuropsychology Section, Vrije Universiteit Amsterdam (E.S.T., R.M.W., J.F.d.K., J.O.); Department of Pediatrics, Emma Children's Hospital, Academic Medical Center (J.B.v.G., R.M.v.E., J.O.); Department of Pediatrics, Vrije Universiteit Medical Center (J.B.v.G., J.O.), Amsterdam; and Nutricia Research, Utrecht (R.M.v.E.), the Netherlands

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