(Abstracted from Am J Obstet Gynecol 2018;218:287–293.e1)
Several randomized studies have found contradictory results while examining the possibility of preventing preeclampsia with a prophylactic daily dose of aspirin. Preeclampsia is a major cause of morbidity and mortality in mothers and their newborns, and it can have particularly adverse consequences if associated with preterm birth.
Harris Birthright Research Centre of Fetal Medicine, Fetal Medicine Research Institute, King’s College Hospital, London, United Kingdom (S.R., K.H.N.); and Departments of Obstetrics and Gynecology and Social and Preventive Medicine, Faculty of Medicine, Université Laval, Quebec City, Quebec, Canada (E.B.)