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Transfer of Fresh Versus Frozen Embryos in Ovulatory Women

Shi, Yuhua; Sun, Yun; Hao, Cuifang; Zhang, Heping; Wei, Daimin; Zhang, Yunshan; Zhu, Yimin; Deng, Xiaohui; Qi, Xiujuan; Li, Hong; Ma, Xiang; Ren, Haiqin; Wang, Yaqin; Zhang, Dan; Wang, Bo; Liu, Fenghua; Wu, Qiongfang; Wang, Ze; Bai, Haiyan; Li, Yuan; Zhou, Yi; Sun, Mei; Liu, Hong; Li, Jing; Zhang, Lin; Chen, Xiaoli; Zhang, Songying; Sun, Xiaoxi; Legro, Richard, S.; Chen, Zi-Jiang

Obstetrical & Gynecological Survey: April 2018 - Volume 73 - Issue 4 - p 213–214
doi: 10.1097/OGX.0000000000000546
GYNECOLOGY: INFERTILITY/REPRODUCTIVE TECHNOLOGIES
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(Abstracted from N Engl J Med 2018;378:126–136)

A previous randomized controlled trial involving women with polycystic ovary syndrome (PCOS) compared fresh-embryo transfer with elective freezing of all embryos followed by frozen-embryo transfer. The data showed that frozen-embryo transfer had a higher live-birth rate in these women compared with fresh-embryo transfer. Whether frozen-embryo transfer also increases live-birth rates among ovulatory women with infertility without PCOS is uncertain.

The Center for Reproductive Medicine, Shandong Provincial Hospital–Shandong University, Key Laboratory of Reproductive Endocrinology of Ministry of Education, and National Research Center for Assisted Reproductive Technology and Reproductive Genetics (Y. Shi, D.W., Z.W., M.S., H. Liu, J.L., L.Z., Z.-J.C.), and Center for Reproductive Medicine, Qilu Hospital of Shandong University (X.D.), Jinan; Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, and Shanghai Key Laboratory of Assisted Reproduction and Reproductive Genetics (Y. Sun, Z.-J.C.), and Shanghai Jiai Genetic and IVF Center, Obstetrics and Gynecology Hospital, Fudan University (X.S.), Shanghai; Center for Reproductive Medicine of Yantai Yuhuangding Hospital, Yantai (C.H.); Center for Reproductive Medicine, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjin (Y. Zhang); Department of Reproductive Endocrinology, Women's Hospital (Y. Zhu, D.Z.), and Center for Reproductive Medicine (S.Z.), School of Medicine, Zhejiang University, Hangzhou; Affiliated Hospital of Qingdao University (X.Q.) and Center for Reproductive Medicine, Qingdao Women and Children's Hospital–Qingdao University (Y. Zhou), Qingdao; Center for Reproduction and Genetics, Suzhou Municipal Hospital, Suzhou (H. Li); Department of Reproductive Medicine, First Affiliated Hospital of Nanjing Medical University–Jiangsu Province Hospital, Nanjing (X.M.); Reproductive Medicine Center of Jinghua Hospital, Shenyang (H.R.); Center for Reproductive Medicine, Wuhan University, Wuhan (Y.W.); Reproductive Medicine Research Center, 6th Affiliated Hospital of Sun Yat-sen University (B.W.), Center for Reproductive Medicine, Women and Children's Hospital of Guangdong Province (F.L.), and Center for Reproductive Medicine, Sun Yat-sen Memorial Hospital of Sun Yat-sen University (X.C.), Guangzhou; Center for Reproductive Medicine, Maternal and Child Health Care Hospital of Jiangxi Province, Nanchang (Q.W.); Center for Assisted Reproduction, Northwest Women and Children's Hospital, Xi'an (H.B.); Center for Reproductive Medicine, Beijing Chaoyang Hospital, Beijing (Y.L.), China; Department of Biostatistics, Yale University School of Public Health, New Haven, CT (H.Z.); and Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey, PA (R.S.L.)

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