(Abstracted from Pediatrics 2017;140(5):e20172695)
Cord blood transplantation provides an array of treatment possibilities, from transplanting hematopoietic stem cells in children to the definitive treatment of certain hematological malignancies, immunodeficiencies, metabolic diseases, and hemoglobinopathies. Cord blood is noninvasively gathered from the placenta of newborn infants that would otherwise be discarded.
Department of Pediatrics and Pathology and Immunology, College of Medicine, Baylor University and Section of Immunology, Allergy, and Rheumatology, Texas Children's Hospital, Houston, TX (W.T.S.); Children's Health, University of California, San Francisco, and Benioff Children's Hospital, San Francisco, CA (B.H.L.); Department of Pediatrics, Medicine, Pathology, Microbiology and Immunology, and Cell Biology and Anatomy, Maria Fareri Children's Hospital and New York Medical College, Valhalla, NY (M.S.C.); and Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD (L.D.N.)