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A Case Report of Human Granulocytic Anaplasmosis (Ehrlichiosis) in Pregnancy and a Literature Review of Tick-Borne Diseases in the United States During Pregnancy

Qasba, Neena MD*; Shamshirsaz, Amirhoushang A. MD; Feder, Henry M. MD; Campbell, Winston A. MD§; Egan, James F. MD; Shamshirsaz, Alireza A. MD**

Obstetrical & Gynecological Survey: December 2011 - Volume 66 - Issue 12 - p 788-796
doi: 10.1097/OGX.0b013e31823e0d0e

There is paucity of data regarding tick-borne diseases during pregnancy. Here, we report a case of human granulocytic anaplasmosis during pregnancy with successful treatment and a favorable neonatal outcome. We also review diagnosis, treatment, and outcomes of published case reports from 1983 to 2010 of human granulocytic anaplasmosis, Lyme disease, babesiosis, and human monocytic ehrlichiosis in the United States.

Target Audience: Obstetricians and Gynecologists and Family Physicians

Learning Objectives: After the completing the CME activity, physicians should be better able to diagnose tick-born diseases, implement best treatment options during the pregnancy, and assess the neonatal outcomes.

*Resident, Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN; †Resident, Department of Obstetrics and Gynecology, Saint Francis Hospital and Medical Center, Hartford, CT; ‡Professor/Clinical, Department of Family Medicine, §Professor/Clinical, Interim Chair and Head of the Division of Maternal-Fetal Medicine, ¶Professor/Clinical, Department of Obstetrics and Gynecology, and **Senior Fellow, Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Connecticut, Farmington, CT

Chief Editor's Note: This article is part of a series of continuing education activities in this Journal through which a total of 36 AMA/PRA Category 1 Credits™ can be earned in 2011. Instructions for how CME credits can be earned appear on the last page of the Table of Contents.

The authors, faculty and staff in a position to control the content of this CME activity and their spouses/life partners (if any) have disclosed that they have no financial relationships with, or financial interest in, any commercial organizations pertaining to this educational activity.

An abstract with some of the data contained in this article was presented as poster at the 38th Annual Scientific Meeting of the Infectious Diseases Society for Obstetrics and Gynecology (IDSOG); August 11–13, 2011; Chicago, IL.

Correspondence requests to: Alireza A. Shamshirsaz, MD, MSCTR, Department of Obstetrics and Gynecology, University of Connecticut, 263 Farmington Ave, Farmington, CT 06030. E-mail:

© 2011 Lippincott Williams & Wilkins, Inc.