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Magnesium Requirements in Children

Recommendations for Reevaluation and Comparison With Current Evidence for Adults

Cao, Sisi PhD; Hodges, Joanna K. PhD; McCabe, Linda D. MSc; Weaver, Connie M. PhD

doi: 10.1097/NT.0000000000000363
Nutrition Science
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Magnesium (Mg), a cofactor in 300 enzymes, is essential for energy transfer and adequate vitamin D status and plays an important structural role with 60% of bodily reserves residing in bone. The Food and Nutrition Board recommendations for dietary intake of Mg, the Dietary Reference Intakes, have not been updated since 1997. Current recommendations for children were set based on an intake producing positive Mg balance. Population-based studies showed that the average intakes in children are suboptimal relative to the current recommendation. Newer evidence suggests Mg requirement should be related to body size. Other potential modifying factors of Mg requirements include calcium and sodium intake and chronic disease state. Future research is needed to refine public health recommendations for Mg and to establish the new Dietary Reference Intakes category of Chronic Disease Risk Reduction level for Mg, especially for children.

Sisi Cao, PhD, is a post-doctoral associate conducting research on calcium effect on health in Department of Nutrition Science, Purdue University, West Lafayette, Indiana.

Joanna K. Hodges, PhD, was a post-doctoral associate in Department of Nutrition Science, Purdue University, West Lafayette, Indiana is currently a postdoctoral researcher conducting studies on the metabolism and health effects of micronutrients and dietary phytochemicals in the Department of Human Sciences, The Ohio State University, Columbus, Ohio.

Linda D. McCabe, MSc, is a research associate with a Master of Science degree in Statistics in Department of Nutrition Science, Purdue University, West Lafayette, Indiana.

Connie M. Weaver, PhD, is Distinguished Professor Emerita in Department of Nutrition Science, Purdue University, West Lafayette, Indiana.

Correspondence: Connie M. Weaver, PhD, Purdue University, 745 Agriculture Mall Dr, West Lafayette, IN 47907 (weavercm@purdue.edu).

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