FeatureChronic fatigue syndrome What nurses need to knowBush, Marianne BS, RN Author Information Marianne Bush is an RN contractor for a national wellness company. The author has disclosed no financial relationships related to this article. Nursing: April 2020 - Volume 50 - Issue 4 - p 50-54 doi: 10.1097/01.NURSE.0000657068.67389.47 Buy Metrics AbstractIn Brief Chronic fatigue syndrome (CFS) is a long-term, often misunderstood disorder that involves the nervous, immune, metabolic, endocrine, and digestive systems. This article describes the pathophysiology of CFS, signs and symptoms of CFS in adults, diagnostic criteria for CFS, and nursing considerations for patients with CFS. This often-misunderstood disorder affects multiple body systems. Learn about signs and symptoms in adults, diagnostic criteria, treatment, and patient education. Wolters Kluwer Health, Inc. All rights reserved