Original ArticlesWhole-body single photon emission computed tomography/computed tomography for assessment of oncological bone disease – is an extended field of view (from vertex to toes) of clinical value?Komber, Hend; Redman, Stewart; Graham, Richard; Anane-Adusei, Sarah; Little, David Author Information Department of Radiology, Royal United Hospitals NHS Trust, Combe Park, Bath, Avon, BA1 3NG Received 23 September 2022 Accepted 7 November 2022. Correspondence to Hend Komber, Department of Radiology, Royal United Hospitals, Combe Park, Bath, Avon, BA1 3NG, UK, Tel: +44 1225 428331; e-mail: [email protected] Nuclear Medicine Communications 44(2):p 131-136, February 2023. | DOI: 10.1097/MNM.0000000000001647 Buy Metrics Abstract Objectives Whole-body single photon emission computed tomography/computed tomography (WB-SPECT/CT) is useful for diagnosing bone metastases. When performed on a dual-headed gamma camera, this may cover from clavicles to proximal femurs due to time constraints. In contrast, the novel 360o cadmium-zinc-telluride scanner can perform WB-SPECT/CT (from vertex to toes) in approximately 20 min. The aim was to assess the prevalence of additional findings above the clavicles and below the lesser trochanters and the prevalence of incidental findings in the CT component. Methods Retrospective study of 117 WB-SPECT/CT scans for oncological bone assessment over a 4-month-period. Scan analysis was performed by two independent experienced radionuclide radiologists. Results The male:female ratio was 71:46 and the mean patient age was 68 years. The primary malignancies were predominantly prostate 65/117 (55.6%) and breast 40/117 (34.2%). There were additional findings of malignancy above the clavicles in 16/116 scans (13.8%) and below the lesser trochanters in 16/117 scans (13.7%). Two cases in the ‘above the clavicles’ group were suspected solitary metastases, whereas four cases in the ‘below lesser trochanters’ group were bone metastases at risk of pathological fracture. Incidental findings of clinical significance included suspected new malignancy in 11/117 (9.4%). Conclusion A WB-SPECT/CT (from vertex to toes) oncological bone protocol is useful for the detection of additional findings of clinical significance above the clavicles and below the lesser trochanters. Reviewing and reporting the CT findings in SPECT/CT is important. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.