Review ArticleThe effects of pharmacological interventions, exercise, and dietary supplements on extra-cardiac radioactivity in myocardial perfusion single-photon emission computed tomography imagingMolavipordanjani, Sajjada; Abedi, Seyed Mohammada; Hosseinimehr, Seyed Jalalb; Fatahian, Alirezac; Mardanshahi, AlirezaaAuthor Information aDepartment of Radiology and Nuclear Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences bDepartment of Radiopharmacy, Faculty of Pharmacy, Pharmaceutical Sciences Research Center, Mazandaran University of Medical Sciences cDepartment of Cardiology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Received 25 January 2020 Accepted 3 May 2020 Correspondence to Alireza Mardanshahi, MD, Mazandaran University of Medical Sciences, Heart Hospital of Sari, Sari 48175-866, Iran, Tel/fax: +98 11 3354 3089; e-mail: email@example.com Nuclear Medicine Communications: September 2020 - Volume 41 - Issue 9 - p 841-847 doi: 10.1097/MNM.0000000000001226 Buy Metrics Abstract Myocardial perfusion imaging (MPI) as an imaging modality plays a key role in the monitoring of patients with cardiovascular disease. MPI enables the assessment of cardiovascular disease, the effectiveness of therapy, and viable myocardial tissue. However, MPI suffers from some downfalls and limitations, which can influence its clinical applications. These limitations can arise from the patient’s condition, equipment, or the actions of the technologist. In this review, we mainly focused on the different effective parameters on radioactivity uptake of organs including liver, intestines, stomach, and gall bladder and how they affect the quality of the acquired images in nuclear medicine. More importantly, we cover how different suggested medicines, foods and exercise alleviative this problem. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.