Original ArticlesComparison of Lutetium-177 tin colloid and Rhenium-188 tin colloid radiosynovectomy in chronic knee arthritisShamim, Shamim Ahmeda; Arora, Geetanjalia; Jha, Pragatia; Gupta, Priyankaa; Behera, Abhisheka; Mukherjee, Anirbana; Prabhu, Meghnaa; Ansari, Mohammad Tahirb; Vyas, Surabhic; Bal, ChandrasekharaAuthor Information Departments of aNuclear Medicine bOrthopedics cRadiodiagnosis, AIIMS, New Delhi, India Received 16 February 2020 Accepted 8 April 2020 Correspondence to Dr. Shamim Ahmed Shamim, MD, Department of Nuclear Medicine, AIIMS, New Delhi, India, Tel: +91 11 26544903; fax: +91 11 26588641; e-mail: email@example.com Nuclear Medicine Communications: August 2020 - Volume 41 - Issue 8 - p 721-726 doi: 10.1097/MNM.0000000000001210 Buy Metrics Abstract Objective To assess the role of Lutetium-177(Lu-177) tin colloid for radiosynovectomy and compare it with Rhenium-188 (Re-188) tin colloid radiosynovectomy for alleviation of pain in patients with chronic inflammatory arthritis of knee. Methods Patients of chronic inflammatory arthritis of the knee underwent pretherapeutic evaluation in a form of knee ultrasonogram, bone scan and clinical evaluation. Fifty-seven recruited patients were allocated at random to receive either intraarticular injections of Lu-177 tin colloid or Re-188 tin colloid. Eventually, 27 patients received Re-188 tin colloid and 30 patients received Lu-177 tin colloid. The joint was then immobilized for 2 days. Response evaluation was done using knee ultrasound, bone scan and clinical findings. Result Of 30, 20 patients responded to radiosynovectomy in the Lu-177 tin colloid group compared to 21/27 patients in the Re-188 tin colloid group. Conclusion Lu-177 tin colloid is an effective alternative to Re-188 tin colloid for radiosynovectomy in patients with chronic inflammatory knee arthritis. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.