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The negative correlation between energy consumption and communication efficiency in motor network

Sun, Xia,b; Zhao, Shujuna; Liang, Shengxianga,b,e; Feng, Tinga,b; Li, Panlonga,b; Zhang, Tianhaob,c; Huang, Qib,c; Liu, Huab,c,d; Nie, Binbinb,c,d; Shan, Baocib,c,d

Nuclear Medicine Communications: May 2019 - Volume 40 - Issue 5 - p 499–507
doi: 10.1097/MNM.0000000000001001
ORIGINAL ARTICLES
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Objective Motor network plays an important role in people’s daily lives. However, until now, the energy consumption mechanism of motor network remains unclear. In this study, we aimed to investigate the energy consumption of motor network.

Materials and methods Fluorine-18-fluorodeoxyglucose PET ([18F]FDG PET) data of 81 healthy male Sprague-Dawley rats were included in this study. Metabolic motor network was constructed on the basis of group independent component analysis. Properties of motor network such as degree and nodal efficiency were investigated using graph theory-based analysis. Furthermore, the relationships between [18F]FDG standardized uptake value ratio and these properties of each node were investigated.

Results A motor network comprising of the following 11 regions were found: left primary motor cortex, right primary motor cortex, left secondary motor cortex, right secondary motor cortex, left primary somatosensory cortex, right primary somatosensory cortex, left secondary somatosensory cortex, right secondary somatosensory cortex, left insular cortex, right insular cortex, and left orbital cortex. Graph theory-based analysis indicated that right primary somatosensory cortex and left secondary somatosensory cortex were the hubs of motor network, and the nodal efficiency and nodal degree share the same order. Further investigation found a significantly negative correlation between nodal efficiency and [18F]FDG standardized uptake value ratios.

Conclusion This study investigated the energy consumption of motor network and found a relationship between energy consumption and communication efficiency. These results may provide insights into the understanding of energy consumption mechanism underlying motor network.

Video abstract: http://links.lww.com/NMC/A142

aCollege of Physical Science and Technology, Zhengzhou University, Zhengzhou

bBeijing Engineering Research Center of Radiographic Techniques and Equipment, Institute of High Energy Physics, Chinese Academy of Sciences

cSchool of Nuclear Science and Technology, University of Chinese Academy of Sciences, Beijing

dCAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai

eNational-Local Joint Engineering Research Center of Rehabilitation Medicine Technology, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China

Correspondence to Binbin Nie, PhD, Key Laboratory of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China Tel: +86 10 8823 6872; e-mail: niebb@ihep.ac.cn

Received April 26, 2018

Received in revised form November 15, 2018

Accepted February 5, 2019

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