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An update on ‘dose calibrator’ settings for nuclides used in nuclear medicine

Bergeron, Denis E.; Cessna, Jeffrey T.

Nuclear Medicine Communications: June 2018 - Volume 39 - Issue 6 - p 500–504
doi: 10.1097/MNM.0000000000000833

Background Most clinical measurements of radioactivity, whether for therapeutic or imaging nuclides, rely on commercial re-entrant ionization chambers (‘dose calibrators’). The National Institute of Standards and Technology (NIST) maintains a battery of representative calibrators and works to link calibration settings (‘dial settings’) to primary radioactivity standards. Here, we provide a summary of NIST-determined dial settings for 22 radionuclides.

Methods We collected previously published dial settings and determined some new ones using either the calibration curve method or the dialing-in approach.

Results The dial settings with their uncertainties are collected in a comprehensive table.

Conclusion In general, current manufacturer-provided calibration settings give activities that agree with National Institute of Standards and Technology standards to within a few percent.

Physical Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, Maryland, USA

Correspondence to Denis E. Bergeron, PhD, National Institute of Standards and Technology, Gaithersburg, MD 20899-8462, USA Tel: +1 301 975 2282; fax: +1 301 926 7416; e-mail:

Received February 26, 2018

Received in revised form March 5, 2018

Accepted March 6, 2018

Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.