ORIGINAL ARTICLESUK audit of quantitative thyroid uptake imagingTaylor, Jonathan C.a; Murray, Anthony W.a; Hall, David O.b; Barnfield, Mark C.c; O’Shaugnessy, Emma R.d; Carson, Kathryn J.h; Cullis, Jamese; Towey, David J.f; Kenny, BobgAuthor Information aDepartment of Nuclear Medicine, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield bDepartment of Medical Physics and Bioengineering, University Hospitals Bristol NHS Foundation Trust, Bristol cDepartment of Medical Physics, Leeds Teaching Hospitals NHS Trust, Leeds dDepartment of Nuclear Medicine, Poole Hospital NHS Foundation Trust, Poole eDepartment of Clinical Physics and Bioengineering, University Hospitals Coventry and Warwickshire NHS Trust, Coventry fDepartment of Medical Physics, Northampton General Hospital, Northampton gLink Medical Ltd, Bramshill, UK hDepartment of Nuclear Medicine, St Luke’s Hospital, Dublin, Ireland Correspondence to Jonathan C. Taylor, MEng, MSc, Department of Nuclear Medicine, I-Floor, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK Tel: +44 114 271 2779; fax: +44 114 226 8921; e-mail: [email protected] Received January 11, 2017 Received in revised form March 8, 2017 Accepted April 6, 2017 Nuclear Medicine Communications: July 2017 - Volume 38 - Issue 7 - p 608-616 doi: 10.1097/MNM.0000000000000681 Buy SDC Metrics Abstract Aim A national audit of quantitative thyroid uptake imaging was conducted by the Nuclear Medicine Software Quality Group of the Institute of Physics and Engineering in Medicine in 2014/2015. The aims of the audit were to measure and assess the variability in thyroid uptake results across the UK and to compare local protocols with British Nuclear Medicine Society (BNMS) guidelines. Participants and methods Participants were invited through a combination of emails on a public mailbase and targeted invitations from regional co-ordinators. All participants were given a set of images from which to calculate quantitative measures and a spreadsheet for capturing results. The image data consisted of two sets of 10 anterior thyroid images, half of which were acquired after administration of 99mTc-pertechnetate and the other half after administration of 123I-iodide. Images of the administration syringes or thyroid phantoms were also included. Results In total, 54 participants responded to the audit. The median number of scans conducted per year was 50. A majority of centres had at least one noncompliance in comparison with BNMS guidelines. Of most concern was the widespread lack of injection-site imaging. Quantitative results showed that both intersite and intrasite variability were low for the 99mTc dataset. The coefficient of quartile deviation was between 0.03 and 0.13 for measurements of overall percentage uptake. Although the number of returns for the 123I dataset was smaller, the level of variability between participants was greater (the coefficient of quartile deviation was between 0.17 and 0.25). Conclusion A UK-wide audit showed that thyroid uptake imaging is still a common test in the UK. It was found that most centres do not adhere to all aspects of the BNMS practice guidelines but that quantitative results are reasonably consistent for 99mTc-based scans. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.