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Commissioning of a new SeHCAT detector and comparison with an uncollimated gamma camera

Taylor, Jonathan C.; Hillel, Philip G.; Himsworth, John M.

doi: 10.1097/MNM.0000000000000162
Technical Notes

Measurements of SeHCAT (tauroselcholic [75selenium] acid) retention have been used to diagnose bile acid malabsorption for a number of years. In current UK practice the vast majority of centres calculate uptake using an uncollimated gamma camera. Because of ever-increasing demands on gamma camera time, a new ‘probe’ detector was designed, assembled and commissioned. To validate the system, nine patients were scanned at day 0 and day 7 with both the new probe detector and an uncollimated gamma camera. Commissioning results were largely in line with expectations. Spatial resolution (full-width 95% of maximum) at 1 m was 36.6 cm, the background count rate was 24.7 cps and sensitivity at 1 m was 720.8 cps/MBq. The patient comparison study showed a mean absolute difference in retention measurements of 0.8% between the probe and uncollimated gamma camera, and SD of ±1.8%. The study demonstrated that it is possible to create a simple, reproducible SeHCAT measurement system using a commercially available scintillation detector. Retention results from the probe closely agreed with those from the uncollimated gamma camera.

Nuclear Medicine Department, Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK

Correspondence to Jonathan Taylor, MEng, MSc, Nuclear Medicine Department, I-floor, Royal Hallamshire Hospital, Glossop Rd, Sheffield, S10 2JF, UK e-mail:

Received January 28, 2014

Accepted June 3, 2014

© 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins