Original Articles: PDF OnlyFRANKEN N. A.P.; LANGEVELDE, A. VAN; JOURNÉE-DE KORVER, J. G.; BAKKER, C. N.M.; FEITSMA, R. I.J.; VAN DELFT, J. L.; OOSTERHUIS, J. A.; PAUWELS, E. K.J.Nuclear Medicine Communications: October 1985 - p 657-663 Buy Abstract Summary The uptake of 123I-5-iodo-2-thiouracil in melanotic and amelanotic melanoma implanted in Syrian golden hamsters was studied. A selective accumulation was found in the tumours. Uptake of 123ITU in melanotic melanomas was 4 to 5 times the uptake in amelanotic ones. For both tumours high ratios of tumour versus non-tumour were found. The high accumulation of 123ITU in both kinds of tumours and the high tumour versus non-tumour ratios suggest that 123ITU may be a promising radiopharmaceutical for the detection of ocular melanoma. © Lippincott-Raven Publishers.