Posterior Reversible Encephalopathy Syndrome on 18F-FDG PET/CT in a Pediatric Patient With Burkitt’s Lymphoma : Clinical Nuclear Medicine

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Posterior Reversible Encephalopathy Syndrome on 18F-FDG PET/CT in a Pediatric Patient With Burkitt’s Lymphoma

Saad Aldin, Ehab MD; McNeely, Parren MD; Menda, Yusuf MD

Author Information

From the Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.

Received for publication November 1, 2017; revision accepted December 19, 2017.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Ehab Saad Aldin, MD, University of Iowa Hospitals and Clinics, 200 Hawkins Dr, Iowa City, Iowa 52242. E-mail: [email protected].

Clinical Nuclear Medicine 43(3):p 195-198, March 2018. | DOI: 10.1097/RLU.0000000000001979

Abstract

We present a case of posterior reversible encephalopathy syndrome (PRES) in a pediatric patient with Burkitt's lymphoma predominantly involving the bone marrow. 18F-FDG PET/CT scan obtained after the first cycle of chemotherapy, complicated by acute kidney injury, hypertension, tumor lysis syndrome, and lethargy with focal neurological symptoms, showed a favorable marrow and lymph node response but increased FDG uptake in the bilateral frontal and occipital cortical/subcortical regions. Brain MRI was consistent with PRES. The patient was managed with IV hydration and blood pressure control with symptom resolution. This case shows the 18F-FDG uptake pattern of PRES in postchemotherapy setting.

Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.

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