Intense Uptake in Amyloidosis of the Seminal Vesicles on 68Ga-PSMA PET Mimicking Locally Advanced Prostate Cancer : Clinical Nuclear Medicine

Secondary Logo

Journal Logo

Interesting Images

Intense Uptake in Amyloidosis of the Seminal Vesicles on 68Ga-PSMA PET Mimicking Locally Advanced Prostate Cancer

Stephens, Maximilian MBB, BSc; Kim, David Insoo MBBS, BSc; Shepherd, Benjamin MBBS, FRCPA; Gustafson, Sonja FRANZCR; Thomas, Paul BMed, FRACP

Author Information
Clinical Nuclear Medicine 42(2):p 147-148, February 2017. | DOI: 10.1097/RLU.0000000000001460

Abstract

We report a case of benign senile seminal vesicle amyloidosis demonstrating intense 68Ga–prostate-specific membrane antigen (PSMA) uptake on PET/CT. A 68-year-old man underwent staging PSMA PET/CT and MRI for biopsy-proven prostate adenocarcinoma. There was an intense focus of 68Ga-PSMA uptake in the primary malignancy, as well as symmetrical intense uptake in the seminal vesicles bilaterally that was reported as multifocal disease with local invasion. Final histology after radical prostatectomy showed amyloidosis of the seminal vesicles without any evidence of prostate cancer. Care should be taken in the interpretation of seminal vesicle PSMA uptake to avoid overstaging.

Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.

You can read the full text of this article if you:

Access through Ovid