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EBV-Associated T-Cell Lymphoproliferative Disorders Demonstrated on FDG PET/CT in a Patient With Hemophagocytic Lymphohistiocytosis

Hao, Ruirui MD*; Yang, Xu MD; Liu, Zhimou MD; Yang, Jigang MD, PhD

doi: 10.1097/RLU.0000000000002649
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FDG PET/CT was performed in a 20-year-old woman to find the underlying cause of hemophagocytic lymphohistiocytosis. The images revealed hypermetabolic activity in multiple lymph nodes and in the spleen. Lymphoma was suspected. However, the pathology of bone marrow, lymph nodes, and the spleen demonstrated chronic active Epstein-Barr virus–associated T-cell lymphoproliferative disorders.

From the *Department of Medical Healthcare Center, Beijing Friendship Hospital, Capital Medical University

Department of Nuclear Medicine, Beijing Friendship Hospital of Capital Medical University, Beijing, People’s Republic of China.

Received for publication April 1, 2019; revision accepted April 23, 2019.

Conflicts of interest and sources of funding: J.Y. was supported by Beijing Natural Science Foundation (No. 7192041), National Key Research and Development Plan (No. 2017YFC0114003) and National Natural Science Foundation of China (No. 81771860). None declared to all other authors.

Correspondence to: Jigang Yang, MD, PhD, Department of Nuclear Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, China 100050. E-mail:

Online date: June 3, 2019

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