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Detection of Uterine Leiomyosarcoma Peritoneal Lesions by SPECT/CT and ROLL Technique

Manca, Gianpiero MD*; Garau, Ludovico Maria MD*; Romanini, Antonella MD; Rubello, Domenico MD; Nuzzo, Amedeo MD; Barbarello, Linda MD§; Fantechi, Lorenzo MD*; Colletti, Patrick M. MD; Boggi, Ugo MD§; Volterrani, Duccio MD*

doi: 10.1097/RLU.0000000000002725
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We reported the preoperative radio-guided localization of 4 peritoneal metastatic nodules in the case of a 45-year-old woman with uterine leiomyosarcoma. Three lines of chemotherapy were tried, but cardiotoxicity occurred. Within the context of so-called GOSTT (guided intraoperative scintigraphic tumor targeting), preoperative radio-guided localization of peritoneal metastases enabled their subsequent radio-guided excisional biopsy. SPECT/CT allowed for anatomical localization of the hot lesions and generated a 3-dimensional volume-rendering roadmap, facilitating a surgical approach.

From the *Regional Center of Nuclear Medicine

Division of Medical Oncology and Plastic Surgery, Hospital University of Pisa, Pisa

Departments of Nuclear Medicine and PET Center, Radiology, Neuroradiology, Medical Physics, Clinical Pathology, Santa Maria della Misericordia Hospital, Rovigo

§Division of General and Transplant Surgery, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy

Department of Radiology, University of Southern California, Los Angeles, CA.

Received for publication March 26, 2019; revision accepted June 1, 2019.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Domenico Rubello, MD, PET Unit, Department of Nuclear Medicine, S. Maria della Misericordia Rovigo Hospital, Rovigo, Veneto, Italy. E-mail:

Online date: July 15, 2019

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