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Normal Variant 18F-Sodium Fluoride Uptake in the Falx Cerebri Ossification

Usmani, Sharjeel MS, FEBNM, KBNM*,†; Marafi, Fahad KBNM, MBBS, MS; Al Kandari, Fareeda KBNM*; Ahmed, Najeeb FRCR, FRCP

doi: 10.1097/RLU.0000000000002741
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Falx cerebri ossification is an incidental finding. Mostly it is easy to diagnose, but can be challenging in few cases, and should be distinguished from calcified meningioma, hematoma, and meningeal infiltration. We report a case of a 46-year-old woman with breast cancer complaining of back pain. 18F-NaF PET/CT images show focal increase uptake at facet joints of L5/S1 vertebrae and both knees joints, suggesting degenerative disease. There is normal variant 18F-NaF uptake noted in the ossification at the falx cerebri. Recognition of normal and abnormal extraosseous 18F-NaF uptake is important for correct interpretation to avoid unnecessary further investigations.

From the *Department of Nuclear Medicine, Kuwait Cancer Control Center

Jaber Al-Ahmad Molecular Imaging Center, Kuwait City, Kuwait.

Received for publication March 12, 2019; revision accepted June 5, 2019.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Sharjeel Usmani, MS, FEBNM, KBNM, Department of Nuclear Medicine, Kuwait Cancer Control Center, PO Box 1488, 83001 Khaitan, Kuwait City, Kuwait. E-mail:

Online date: July 15, 2019

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