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18F-FDG PET/CT in Bladder Cancer

Tagliabue, Luca, MD; Russo, Giovanna, MD; Lucignani, Giovanni, MD

doi: 10.1097/RLU.0000000000001403
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Urinary clearance of 18F-FDG and variability in bladder wall FDG uptake may hamper the interpretation and limit the use of FDG-PET/CT for imaging bladder tumors. Nevertheless, careful combined evaluation of both CT and FDG-PET images of the urinary tract can provide useful findings. We present 2 cases of bladder cancer detected by FDG-PET/CT. These cases suggest that FDG uptake can be indicative of malignancy in bladder cancer when viewed in conjunction with CT scans and that whole-body FDG-PET/CT scans should always be reviewed with particular attention to the urinary tract because abnormalities suggestive of bladder cancer can be found unexpectedly.

From the *Department of Diagnostic Imaging, Nuclear Medicine Unit, ASST “Santi Paolo e Carlo” University Hospital, Milan; and †Department of Clinical Science, University of Milan, Milan, Italy.

Received for publication February 22, 2016; revision accepted August 26, 2016.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Luca Tagliabue, MD, Department of Diagnostic Imaging, Nuclear Medicine Unit, ASST “Santi Paolo e Carlo” University Hospital, Via A. di Rudinì 8, 20142 Milan, Italy. E-mail: luca.tagliabue@asst-santipaolocarlo.it.

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