18F-FDG PET/CT Findings of Leptomeningeal Metastasis in Nasopharyngeal Carcinoma : Clinical Nuclear Medicine

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18F-FDG PET/CT Findings of Leptomeningeal Metastasis in Nasopharyngeal Carcinoma

Montanarella, Matthew DO; Boldig, Kimberly DO; Natter, Patrick MD; Ozdemir, Savas MD

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Clinical Nuclear Medicine 48(2):p 201-202, February 2023. | DOI: 10.1097/RLU.0000000000004499
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Sagittal T1 (A) and postcontrast T1 fat-saturated (B) MR of the lumbar spine demonstrate an enhancing lesion in the spinal canal at the level of the sacrum (arrow). MIP image of PET/CT (C) and sagittal fused PET/CT (D) demonstrate diffuse FDG-avid spinal leptomeningeal metastasis with SUVmax of 32. The findings are easily discernible on PET/CT.1–8 Also noted are FDG-avid left cervical and supraclavicular nodal metastasis on MIP image. Traditionally, CSF cytology and MRI have been used in the diagnosis of leptomeningeal metastasis.9–11 PET/CT has shown utility in this case by accentuating the extent of disease.


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nasopharyngeal carcinoma; leptomeningeal metastasis; FDG PET/CT

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