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Early and Delayed 18F-FCH PET/CT Imaging in Parathyroid Adenomas

Vellani, Cecilia MD; Hodolič, Marina MD; Chytiris, Spyridon MD; Trifirò, Giuseppe MD; Rubello, Domenico MD; Colletti, Patrick M. MD

doi: 10.1097/RLU.0000000000001466
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Preoperative localization with 99mTc-sestaMIBI or ultrasound is a common prerequisite for successful minimally invasive parathyroid adenoma (PA) surgery. SPECT/CT with 99mTc-sestaMIBI and PET/CT with 18F-FCH offer the possibility of attenuation correction and coregistration of functional and anatomical images providing more accurate PA localization. 18F-FCH PET/CT is used predominantly in patients with prostate cancer and is under investigation in PA. We report the case of a 43-year-old man with early FCH uptake in a cystic PA with delayed washout at 60 minutes.

From the *Nuclear Medicine Unit, Fondazione Salvatore Maugeri, Pavia, Italy; †Nuclear Medicine Research Department, Graz, Austria; ‡Medical Faculty, Palacký University Olomouc, Czech Republic; §Internal Medicine & Endocrinology Unit, Fondazione Salvatore Maugeri, Pavia; ∥Department of Nuclear Medicine, Rovigo Hospital, Rovigo, Italy; and #Department of Radiology, Division of Nuclear Medicine, University of Southern California, Los Angeles, CA.

Received for publication September 8, 2016; revision accepted October 6, 2016.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Patrick M. Colletti, MD, Division of Nuclear Medicine, University of Southern California, Keck Medical Center of USC, 1500 San Pablo Street, 2nd Floor, Imaging, Los Angeles, CA 90033. E-mail:

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